Gwen E. Guglielmi received her B.S. degree (summa cum laude) from Cook College of Rutgers University in 1979 and her M.D. from the University of Pennsylvania School of Medicine in 1983. She served an internship in internal medicine, a residency in diagnostic radiology, and received fellowship in CT/ultrasound and MRI at the Hospital of the University of Pennsylvania. In 1987, she became a diplomate of the American Board of Radiology and the following year received a fellowship at the National Cancer Center in Tokyo, Japan.

Dr. Guglielmi was appointed instructor in radiology at the University of Pennsylvania in 1987 and at the Harvard Medical School one year later. She has been on staff at two Boston-area hospitals, and, since 1992, she has been part of the attending staff at University Medical Center at Princeton (UMCP) and a member of Princeton Radiology Associates.

Dr. Guglielmi is a member of the Radiological Society of North America, the Medical Society of New Jersey, and the Mercer County Medical Society. Her publications include articles in the American Journal of Roentgenology and the Journal of Nuclear Medicine.